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Homemade Greek tzatziki chicken sandwich recipe in pita bread with fresh vegetables and yogurt sauce on a white kitchen counter.

Tzatziki Sandwich Recipe

Fresh Mediterranean Tzatziki Sandwich made with creamy cucumber yogurt sauce, juicy chicken, crisp vegetables, and warm pita. Ready in under an hour, perfect for a healthy and flavorful lunch or dinner.
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Course: Dinner, LUNCH, Main Course
Cuisine: Greek, Mediterranean
Prep Time: 15 minutes
Cook Time: 12 minutes
Chilling tzatziki: 30 minutes
Total Time: 57 minutes
Servings: 4 sandwiches
Calories: 420kcal
Cost: $12

Equipment

  • 1 Box grater For cucumber
  • 1 Clean kitchen towel For squeezing cucumber dry
  • 1 Medium mixing bowl For tzatziki
  • 1 Sharp Chef’s Knife For slicing vegetables & chicken
  • 1 Cast iron skillet or grill pan For chicken & warming pita
  • 1 Meat thermometer Ensure chicken reaches 165°F
  • 1 Parchment paper For wrapping sandwiches
  • Several Food storage containers For storing components

Ingredients

Tzatziki Sauce

  • 1 cup Greek yogurt Full-fat preferred
  • 1 medium Cucumber Grated & squeezed dry
  • 3 cloves Garlic Minced
  • 2 tablespoon Fresh dill Chopped
  • 1 tablespoon Lemon juice Freshly squeezed
  • 2 tablespoon Olive oil Extra virgin
  • ½ teaspoon Salt Adjust to taste
  • ¼ teaspoon Black pepper Freshly ground

Sandwich Assembly

  • 4 pita Pita breads Warmed
  • 2 cups Chicken breast Cooked & sliced
  • 1 cup Cherry tomatoes Halved
  • 1 cup Cucumber Sliced
  • ½ medium Red onion Thinly sliced
  • 1 cup Romaine lettuce Chopped
  • ½ cup Feta cheese Crumbled (optional)
  • ¼ cup Kalamata olives Sliced (optional)

Instructions

  • Grate cucumber and squeeze dry using a towel.
  • Mix yogurt, garlic, dill, lemon juice, olive oil, salt, and pepper to make tzatziki.
  • Chill tzatziki in refrigerator for 30 minutes.
  • Season and grill chicken for 6–7 minutes per side until cooked through (165°F). Rest for 5 minutes.
  • Slice vegetables evenly for sandwich assembly.
  • Warm pita breads on skillet or grill pan for 30 seconds per side.
  • Spread tzatziki on pita, layer chicken, vegetables, feta, and olives.
  • Fold pita and cut sandwich in half. Serve immediately.

Notes

  • Nutrition information is automatically calculated, so should only be used as an approximation.

Nutrition

Serving: 350g | Calories: 420kcal | Carbohydrates: 32g | Protein: 32g | Fat: 18g | Saturated Fat: 5g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 9g | Cholesterol: 75mg | Sodium: 690mg | Potassium: 680mg | Fiber: 4g | Sugar: 6g | Vitamin A: 900IU | Vitamin C: 20mg | Calcium: 180mg | Iron: 2.5mg