Spinach Artichoke Chicken Casserole Recipe
A creamy, cheesy chicken casserole packed with spinach, artichokes, and rich flavors — ready in under 45 minutes. Perfect for busy weeknights and family dinners!
Print Pin Servings: 8 servings
Calories: 435kcal
Cost: $18
Equipment
- 1 9x13 inch baking dish Glass or ceramic for even heat and golden edges
- 1 Large mixing bowl For combining creamy ingredients
- 1 Hand mixer or whisk To smooth out cream cheese mixture
- 1 Heavy-bottomed skillet Ideal for searing chicken evenly
- 1 Meat thermometer Ensures chicken reaches 165°F
- 1 Kitchen towel For squeezing spinach completely dry
- 1 Sharp knife and cutting board For chopping chicken, artichokes, and garlic
- 1 Aluminum foil Prevents cheese from burning while baking
Ingredients
Main Ingredients
- 2 pounds boneless, skinless chicken breasts Cut into bite-sized pieces
- 2 tablespoons olive oil For browning chicken
- 1 teaspoon garlic powder Adds warmth and flavor
- salt and black pepper To taste
- 8 ounces cream cheese Softened for creamy texture
- 1 cup sour cream Substitute Greek yogurt if desired
- 1 cup mayonnaise Or half mayo, half Greek yogurt
- 10 ounces frozen spinach Thawed and squeezed dry
- 14 ounces canned artichoke hearts Drained and chopped
- 3 cloves garlic Minced fresh for best flavor
- 1 teaspoon onion powder Adds depth
- 0.5 teaspoon red pepper flakes Optional, for mild heat
- 2 cups shredded mozzarella cheese For melty, gooey top
- 1 cup grated parmesan cheese Adds nutty, salty flavor
- 0.5 cup Italian breadcrumbs Optional, for crunch
Instructions
- Preheat oven to 375°F and grease a 9x13-inch baking dish.
- Cut chicken into bite-sized pieces, season with garlic powder, salt, and pepper.
- Sear chicken in olive oil for 3–4 minutes per side until lightly golden; transfer to dish.
- In a large bowl, mix softened cream cheese, sour cream, and mayonnaise until smooth.
- Stir in garlic, onion powder, red pepper flakes, spinach, and artichokes.
- Spread creamy mixture evenly over the chicken in the baking dish.
- Top with mozzarella and parmesan; add breadcrumbs if desired.
- Cover with foil and bake 25 minutes; uncover and bake 15–20 minutes more.
- Let casserole rest for 5–10 minutes before serving.
Notes
- Nutrition information is automatically calculated, so should only be used as an approximation.
Nutrition
Serving: 250g | Calories: 435kcal | Carbohydrates: 7g | Protein: 34g | Fat: 30g | Saturated Fat: 12g | Polyunsaturated Fat: 3g | Monounsaturated Fat: 10g | Cholesterol: 115mg | Sodium: 720mg | Potassium: 510mg | Fiber: 2g | Sugar: 3g | Vitamin A: 4200IU | Vitamin C: 7mg | Calcium: 240mg | Iron: 1.6mg